RNA Details
Disease Name
diabetic cardiomyopathy
Tissue
heart
RNA Symbol
Kcnq1ot1
RNA ID
RNA Type
lncrna
Alteration Pattern
up regulation
Species
mus musculus
Detection Methods
dual-luciferase reporter assay
Target
NA
Pathway
NOD-LIKE RECEPTOR SIGNALING PATHWAY
PubMed ID
Title
Silencing long non-coding RNA Kcnq1ot1 alleviates pyroptosis and fibrosis in diabetic cardiomyopathy
Year
2018
Function
Kcnq1ot1/miR-214-3p/caspase-1/TGF-beta signal pathway presents a new mechanism of diabetes cardiomyopathy (DCM) progression and could potentially be a novel therapeutic target.